Keticap.
Our two oral ketamine products are branded Keticap®:
- Keticap® IR is our immediate release capsule formulation.
- Keticap® AD is our abuse deterrent formulation.
Oral Keticap® is an immediate release, abuse-deterrent, capsule formulation of therapeutic ketamine for the treatment of various mood disorders such as Treatment Resistant Depression (TRD) and bipolar depressions.
Keticap® has completed a Phase1 human trial which demonstrated the agent is safe and well tolerated at multiple dose levels where active drug concentrations and clinical activity are also observed.
We are now commencing additional trials – one for the treatment of bipolar depression, and additional studies in patients with other types of depression where the medicine is clinically indicated.
Keticap®-AD is intended to be the first standard prescription form of ketamine available for use as a routine and cost-effective oral medication to treat depression.
Benefits.
Immediate Release
Keticap® is an immediate release treatment, intended to benefit the patient within 50-60 minutes of the capsule being taken orally. This applies to our powder-filled capsule and the abuse-deterrent variation.
Abuse Deterrent
Keticap® abuse-deterrent capsules contain a gel-like substance in which the ketamine is dissolved. This means the drug cannot be manipulated for abusive purposes such as snorting or injecting. The formulation is designed for immediate release, with drug release and absorption into the body within 60 minutes of administration.
Evidence of effects
Our Phase1 study demonstrated Keticap is delivering sufficient levels of ketamine and its major metabolites to have Pharmacodynamic effects. The findings will be confirmed in the upcoming Phase II/III trials in patients.
Clinical Indications.
Depression
Depression is one of the most prevalent mental health disorders, affecting around one in six adults. It can also be known as major depression, major depressive disorder, or clinical depression and is a common but serious mood disorder. It causes severe symptoms that affect how a person feels, thinks, and handles daily activities, such as sleeping, eating, or working.
Bipolar Depression
Bipolar depression episodes occur in patients with bipolar disorder, and these episodes of lowered mood can prevent the patient from carrying out day-to-day tasks. Bipolar depression can be fairly common and few treatment options are available to address these episodes.
Abuse Deterrent.
Strong Patents.
Phase 2 Trials Underway.
Multiple Disease Indications.
Investors & Partners
Patients & Healthcare Professionals
Investors & Partners
Patients & Healthcare Professionals
